Naphthalimide derivatives
Witryna16 cze 2015 · Structure-based design, synthesis and subsequent optimization resulted in the development of a library of 1,8-naphthalimide derivatives, called the Naphthaladyn™ series, with compounds 23 and 29 being the most active (IC 50 of 19.1 ± 0.3 and 18.5 ± 1.7 μM respectively). WitrynaA series of quinoline derivatives as aza analogues of the naphthalene chromophore and a series of “nonfused” tricyclic aromatic systems, in particular 5-arylquinolines and 5- or 6-aryl and heteroaryl naphthalene systems, were synthesized and evaluated for growth-inhibitory properties in several human cell lines. The analysis of quantitative …
Naphthalimide derivatives
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Witryna14 kwi 2015 · All these preliminary results indicated that 1,8-naphthalimide derivatives could act as quite promising standard-red light-emitting materials for OLED applications. You have access to this article WitrynaThe results suggest that, in the case of 1,8-naphthalimide derivatives, radicals derived from quenching of the triplet state by ground-state chromophores are more effective in cleaving DNA than reactive oxygen species or radicals derived from halogen atoms. Publication types Research Support, U.S. Gov't, Non-P.H.S.
Witryna9 paź 2024 · Based on self-assembly, novel electron extraction layers (EELs) composed of naphthalimide (NPI) derivatives are constructed for application in n-i-p perovskite solar cells. Upon molecular energy level modulation, the power conversion efficiencies have been largely improved from 5.4% to 16%. Such low-cost and Witryna22 lut 2024 · Two kinds of naphthalimide derivatives were synthesized and evaluated for in vitro their anti-hepatocellular carcinoma properties. Compound 3a with a fused thiazole fragment to naphthalimide skeleton inhibited cell migration of SMMC-7721 and HepG2, and further in vivo trials with two animal models confirmed that compound 3a …
Witryna12 paź 2009 · The solvatochromic fluorophore 4-N,N-dimethylamino-1,8-naphthalimide (4-DMN) possesses extremely sensitive emission properties due largely to the low intrinsic fluorescence it exhibits in polar protic solvents such as water. This makes it well suited as a probe for the detection of a wide range of biomolecular interactions. … WitrynaAn azide and hydrazine tethered to a naphthalimide analogue was created to selectively react with 5-formyluracil in one system and fluorogenically label 5-formylcytosine in another system. ... Naphthalimide derivatives as multifunctional molecules for detecting 5-formylpyrimidine by both PAGE analysis and dot-blot assays Y. Wang, C. Liu, W ...
Witryna15 wrz 2016 · Many naphthalimide derivatives have been developed into drugs, sensors, and other dyes. In this study, a series of 1,8-naphthalimide derivatives targeting live cell mitochondria were synthesized. Among these probes, Mt-4 was characterized as the best one, with highly specific mitochondrial localization, low …
Witryna6 kwi 2024 · By designing two novel naphthalimide derivatives ( NIB and NIBD ), we experimentally demonstrated the effect of a single formyl group that can efficiently transform an aggregation caused quenching (ACQ) system ( NIB) into an AIEEgenic system ( NIBD) by strengthening the RIM process. fancy e outlineWitryna10 gru 2024 · A series of naphthalimide derivatives as intra and extracellular pH sensors. Biomaterials, 2010, 31 (29): 7411–7422 CAS PubMed PubMed Central Google Scholar Ao X, Bright S A, Taylor N C, Elmes R B P. 2-Nitroimidazole based fluorescent probes for nitroreductase; monitoring reductive stress in cellulo. corepower yoga deerfield scheduleWitrynaFour N-[2-(dimethylamino)ethyl]-1,8-naphthalimide derivatives (ANNs) with different substituents (bromo group, primary amine, secondary amine, and tertiary amine) in the naphthalimide skeleton have been synthesized and can be used as one-component free radical photoinitiators or incorporated into multi-component photoinitiating systems for … corepower yoga class pack pricingfancy entree ideasWitryna1 gru 2024 · BTA derivatives possesses broad spectrum biological activities such as anticancer, antioxidant, anti-inflammatory, anti-tumour, antiviral, antibacterial, anti-proliferative, anti-diabetic,... fancy e outlookWitryna27 sie 2024 · Thus, many new naphthalimide derivatives have been developed as anticancer agents. 9, 10 We previously synthesized several naphthalimide derivatives and found them to exhibit cytotoxic effects on B16F10 melanoma cells and reduce lung metastasis at least partly through the inhibition of topo II activity. 15, 16 Among the … fancy entertainment miamiWitrynaUsing water-soluble 1,8-naphthalimide derivatives, the mechanisms of photosensitized DNA damage have been elucidated. Specifically, a comparison of rate constants for the photoinduced relaxation of supercoiled to circular DNA, as a function of dissolved halide, oxygen and naphthalimide concentration, has been carried out. fancy entertainment michigan