Thbs1 mcf7
Web8 Mar 2024 · THBS1 is a marker of high-grade glioma. a Immunohistochemistry (IHC) of THBS1 in patient samples from grade II astrocytomas and oligodendrogliomas (upper … Web5 Dec 2024 · To clarify the function of TSP1 in exosomes released by breast cancer cells, we established MDA-MB-231/sh- THBS1, a TSP1-knockdown MDA-MB-231 cell line and MCF7/ THBS1, a TSP1 stably expressing MCF7 cell line, and prepared exosomes derived from the transfectants as well as parent breast cancer cells ( Figure 4 C and Figure S5 ).
Thbs1 mcf7
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Web29 Mar 2024 · The thrombospondin family comprises of five multifunctional glycoproteins, whose best-studied member is thrombospondin 1 (TSP1). This matricellular protein is a potent antiangiogenic agent that inhibits endothelial migration and proliferation, and induces endothelial apoptosis. Studies have demonstrated a regulatory role of TSP1 in cell … Web9 Oct 2024 · Conversely, the mRNA and protein expression of A1BG, THBS1 and TPM4 were all reduced in MCF-7 cells. Hence, allicin induces cell cycle arrest and apoptosis in breast cancer cells through p53 activation but it effects on the expression of p53-related biomarkers were dependent upon the specific type of breast cancer involved. These …
Web22 Apr 2024 · In the current study, we identified Thbs1 as an extracellular regulator of YAP, which is induced by mechanical stress and acts through FAs independent of actin remodeling. Mechanistically, Thbs1 binds integrin αvβ1 and strengthens FAs, aiding in translocation of YAP to the nucleus. WebDownload scientific diagram Exogenous THBS1 and TNC protected MCF-7 cells against proliferation inhibition by docetaxel through activating integrin β1/mTOR pathway and deregulating cell cycle ...
WebCulturing conditions highly affect DNA methylation and gene expression levels in MCF7 breast cancer cell line In Vitro Cell Dev Biol Anim. 2024 May;54 ... RASSF1, and THBS1 … Web7 Feb 2024 · THBS1 is an adhesive glycoprotein that mediated cell-to-cell and cell-to-stromal interaction and is associated with platelet aggregation, angiogenesis, and tumorigenesis ( 11 – 13 ). Furthermore, in order to identify the results of expression profiles, we verified and analyzed the expression of THBS1 in the 116 patients and 9 healthy controls.
WebDetailed information about the celline expression of THBS1 on RNA level in MCF7. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are …
Web9 Apr 2024 · We demonstrate that epithelium-derived breast cancer cell MCF7 presents apical-out phenotypes in the liquid culture with LA717, whereas apical-in phenotypes in … shlomo hirscheyWebTHBS1is not a tumor suppressor gene, but the regulation of its expression in malignant cells by oncogenes and tumor suppressor genes mediates some of their effects on … shlomo hechthttp://cancer-genetics.org/THBS1.htm rabbit chew on cablesshlomo hestrinWeb18 May 2024 · The Prostate Specific Antigen (PSA) test suffers from low specificity for the diagnosis of Prostate Cancer (PCa). We originally discovered two cancer-related proteins thrombospondin-1 (THBS1) and cathepsin D (CTSD) using a mass-spectrometry-based proteomics approach. The two serum proteins were shown to improve the diagnosis of … shlomo hellerWeb27 Aug 2024 · Purpose: Thrombospondin 1 ( THBS1) is an endogenous inhibitor of angiogenesis, but it also promotes tumor invasion, metastasis, and immune response in … rabbit chicharonWeb5 Dec 2024 · Essentially the same phenomenon was found between MCF7/THBS1 and MCF7 cell groups (Figure 6 C,D). The results collectively demonstrated that breast cancer … rabbit chew toys for teeth